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doi: 10.1152/japplphysiol.01222.2011

Retrieved May 27, 2020

The claudins: from tight junctions to biological systems

Numbness, tingling in hands, legs and feet (as a result of nerve damage which is triggered by low oxygen levels in cells) Muscle weakness and coordination problems Mental problems such as depression, anxiety, memory loss, changes in behaviour Fertility issues and recurring early miscarriage So if you have any of the above symptoms it would be worth getting your B12 levels tested by your health practitioner as you may need supplementation or B12 injections for more severe cases