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Hemolysis causes a decrease in HbA1c level but not in glycated albumin or 1,5-anhydroglucitol level

With over 50 million individuals currently affected by dementia worldwidea number projected to double by 2050there is a critical need for novel, mechanism-based interventions, particularly in the absence of curative therapies (Sexton et al., 2022)

7,77 Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) Chronic kidney disease-mineral and bone disorder (CKD-MBD) is a common complication in which one or more of the following occur due to the loss of proper regulation by the kidneys: Abnormal bone mineralization, strength, growth, and turnover Calcification of non-bone tissues, including blood vessels Irregularities in vitamin D, calcium, phosphorus, fibroblast growth factor-23, and parathyroid hormone metabolism Each of these abnormalities is associated with a high risk of mortality, primarily attributable to the cardiovascular consequences

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These alterations include hippocampal atrophy, reduced gray matter volume in the prefrontal cortex, impaired synaptic density, and disruptions in neural network connectivity