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The modulation of the gut microbiota by mycotoxins can also lead to SIFO (Small Intestine Fungal Overgrowth) or Candida overgrowth

Continuous long-term use has not been adequately studied, and the safety of prolonged dosing remains unknown

AMPK can be thought of as a key contributing factor of HIF-1 functions in response to H 2 O 2 , and it may also play a role in the complex HIF-1 regulatory mechanisms (Figure 4) [57]