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however, decreases in TSH and T4 are seen in more prolonged or severe illness

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These events not only damage the cell and plasma membranes but also induce the formation of protein pores in the cell membrane, disrupting intracellular homeostasis [185, 186]

In a study of fluoride-induced apoptosis in follicular granulosa cells, results showed that mitochondria in granulosa cells exhibited typical features of ferroptosis, such as reduced mitochondrial volume and reduced mitochondrial crags [51]

61 AF innervation was increased in injured mice, but no nerve fibers were observed deep into any of the degenerative discs of these mice