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Description

It is the only known circulating orexigenic hormone and signals both on vagal afferents and in the arcuate nucleus where it powerfully enhances NPY orexigenic signaling (176, 177)

PMID: Summary Keywords adenosine, CD38, daratumumab, immunosuppression, immunotherapy, inosine, isatuximab, multiple myeloma Citation Horenstein AL, Frerichs KA, Faini AC, van de Donk NWCJ and Malavasi F (2026) Modulating CD38 enzymatic activity during antibody-based immunotherapy in multiple myeloma: a basic science perspective