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Typical cycles run four to eight weeks, sometimes longer for chronic tendon issues

Early detection and treatment prevent irreversible neurological complications

"If the cracks are accompanied by a sore tongue its a less common sign of a vitamin B deficiency

(2008) Cyanocobalamin may be beneficial in the treatment of recurrent aphthous ulcers even when vitamin B12 levels are normal

[31] No allergic effects against OHCbl were seen in a study at dosages below 2.5 gm although higher dosages from 5 g to 7.5g showed effects in few volunteers ranging from itching, facial erythema, swelling, eye reddening, shivering, dyspnoea, facial oedema, and spontaneous exanthema