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Because GDF11 and MSTN circulate mostly in inactive, latent forms 35 , their local activation patterns and localization of antagonists may largely contribute to distinct physiological effects of GDF11 and MSTN

Dihexa is structurally derived from angiotensin IV, a peptide hormone that has been implicated in various physiological processes, including cognition and memory

BDNF is an important neurotrophin with a role in neurogenesis, neuronal survival, learning and memory, as well as in regulation of body weight and energy homeostasis 42