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One small additional consideration is tolerability, particularly around progesterone formulation

For instance, the loss of SWI/SNF function can lead to the physical silencing of key tumor suppressor pathways, thereby enhancing therapeutic resistance [55]

Senin LL, Al-Massadi O, Folgueira C, Castelao C, Pardo M, Barja-Fernandez S, Roca-Rivada A, Amil M, Crujeiras AB, Garcia-Caballero T, Gabellieri E, Leis R, Dieguez C, Pagotto U, Casanueva FF, Seoane LM