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It has been found that the Vina docking calculations are useful to predict the binding modes, orientations, and conformations of small molecule inhibitors within the catalytic domain of the target protein

Orr has a patent Biosignature and therapeutic approach for neuronal senescence pending

[51] Recently, KSL0608-Se, a photoactivable senolytic drug capable of single cell-resolution senolysis was designed using beta-galactosidase (-gal) targeted prodrug and target-site anchoring strategies