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Parameters were collected, some of which include heart rate (HR), left ventricular end-diastolic diameter (LVIDd), left ventricular end-systolic diameter (LVIDs), end-diastolic interventricular septal wall thickness (IVSd), left ventricular end-diastolic posterior wall (LVPWd), left ventricular fractional shortening (LVFS), left ventricular ejection fraction (LVEF), peak Doppler blood inflow velocity across the mitral valve during early diastole (E), peak Doppler blood inflow velocity across the mitral valve during late diastole (A), and peak tissue Doppler of myocardial relaxation velocity at the mitral valve annulus during early diastole (E)

However, they can still impact the endocrine system, insulin sensitivity, and IGF-1 axis with prolonged or high-dose use

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They generally develop over time, days, not weeks

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