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Human pharmacokinetics, adverse event frequencies, and drug interactions are unknown

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In the U.S., states that offer and cover PrEP options have reported a 38% decrease in new infections, whereas states that dont make PrEP as available saw a 27% increase in infections from 2012 to 2022, according to a recent report published in the Lancet HIV

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Such improvement promotes lipogenesis in fat (recall that IGF-1 could maintain cytokine homeostasisanti-inflammatory effects-, and thus protection from mild inflammation as a consequence of obesity)