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Aggresomes, inclusion bodies and protein aggregation

Indeed, several studies have proposed that DAM contribute to the clearance of neuronal debris, including synaptic structure, a function inferred from their transcriptional profile as described by Keren-Shaul et al

10.1016/j.scitotenv.2018.07.363 104 ZulkifliM.SpelbringA

Addressing the rising incidence of azole-resistant Aspergillus fumigatus , researchers also developed novel inhibitors targeting Af DHODH, a key enzyme in pyrimidine biosynthesis, yielded 13 candidate molecules, with two demonstrating sub-100 M activity in vitro ( Li K

This complex interaction highlights ferroptosis as a central mechanism linking various PD-related pathogenic processes