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Previous exposure to TNF inhibitors other than Humira was permitted in up to 25% of patients

In recent years, ferroptosis, a regulated form of iron-dependent cell death, has emerged as a crucial contributor to AD progression

Kanarek, R

Yes, it is generally safe

Importantly, targeting of MK-801 to GLP-1 receptor-expressing brain regions circumvents adverse physiological and behavioural effects associated with MK-801 monotherapy