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DHODH-mediated Ferroptosis Defence Is a Targetable Vulnerability in Cancer

Especially, high fat diet with high iron induced higher ferritin contents compared with control/high-fat group at the same time point, and DFO decreased the ferritin levels, indicating the occurrence of iron overload induced by high fat or high iron diets, and even more iron overload by synergistic administration of high fat and high iron diet

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2005 Jun;90(6):3472-8