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Orvosi hetilap 153 (15): 574585

In Calcium Transport Elements in Plants pp

In the context of GH and IGF-I physiology it can be concluded that 1) during childhood and adolescence the combined actions of GH and IGF-I in the presence of sufficient nutrition promote longitudinal growth and somatic maturation, 2) continued excess IGF-I activity in adulthood increases the risk for cardiovascular and neoplastic diseases and hence reduces longevity, 3) calorie restriction, which suppresses IGF-I activity and stimulates GH secretion, may promote longevity in human adults (82)

Clin Cancer Res 24(24):6195-6203, 2018

Materials The substances examined in this investigation, together with their molecular formulae and sources, are presented in Table 1