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Identification and Characterisation of Human xCT That Co-Expresses, With 4F2 Heavy Chain, the Amino Acid Transport Activity System Xc

Cell Metab (2015) 21(2):28698

1) Cell type- and nephron segment-specific susceptibility: The kidney is a highly heterogeneous organ, with distinct nephron segments [PT, distal tubule (DT), collecting duct (CD)] and cell types (podocytes, mesangial cells, interstitial fibroblasts, and endothelial cells) exhibiting divergent ferroptosis susceptibility

Libraries were prepared using the Kapa HTP kit (Illumina, San Diego, CA, United States) and capture was performed using the SeqCap EZ Human Exome Library v3.0 (Roche NimbleGen Madison, WI, United States)

National Institute of Diabetes and Digestive and Kidney Disease