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Discussion Currently, in the clinical setting, there is a lack of effective early and mid-term treatment options for lumbar intervertebral disc degeneration

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139 Because the use of a common class of cholesterol-lowering drugs called statins lowers CoQ10 production, patients taking statins in particular may benefit from supplementing with CoQ10

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SGLT-2 inhibitors and thiazolidinediones may also be used concurrently, though patients should be monitored for any unexpected interactions or adverse effects