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Gut Microbes 14:1997294

Improvement of spermatogenesis in adult cryptorchid rat testis by intratesticular infusion of lactate

558 In two small, randomized, double-blind, placebo-controlled crossover trials, a single 500 mg dose of mango leaf extract standardized to 60% mangiferin was shown to improve reaction time by nearly 5% compared with placebo and lessen fatigue by nearly 50% compared to baseline

These results suggest ROS may have the potential to amplify mitophagy-ferroptosis signals through a positive feedback mechanism

Various post-translational modifications (PTMs) such asphosphorylation, ubiquitination, acetylation and nitrationalter -syns biochemical properties (Yoo et al