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Although clinical trials are limited, the evidence suggests that B12 injections at a dose of at least 500 g three times per week for 2 weeks are effective in relieving chronic low back pain

SAPONINS Saponins, which are glycosides, exhibit both hydrophobic and hydrophilic characteristics and they are the ones that are distinguished by the existence of a hydrophobic aglycone (sapogenin) that is connected to either a single or multiple hydrophilic sugar chains

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Hydroxocobalamin licensed in the UK for intramuscular injection every 3 months, or 2 months with neurological involvement