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Salvianolic acid A (Sal A) contains two molecules of caffeic acid and one molecule of danshensu that is capable of enhancing homocysteine transsulfuration, which led to the hypothesis that Sal A has activatory effect on transsulfuration pathway and this effect may have beneficial effects on both homocysteine and redox status in hyperlipidemia

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And all the drugs that work on this are targeting that receptor

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The blood brain barrier (BBB) is a natural protective layer of cells and capillaries creating a selective permeable barrier between the interstitium of the brain and the bloodstream