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it signals a chemical change

One article deals with treatment of autoimmune myocarditis in Graves' disease, which is an immune system disorder that results in overproduction of thyroid hormones (hyperthyroidism) (Wu et al.)

I wanted to share with you some excerpts from this paper, which you can also find in full here

6 BakerJ.HardyM

However, extensive skin damage, such as that seen in diabetic pathologies which frequently result in chronic wounds, can severely disrupt the normal healing process, driving research in skin tissue engineering to focus on strategies that accelerate repair and restore function