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These fluid markers can be sampled longitudinally with minimal invasiveness, and combining them with TSPO-PET or other microglial/astrocytic imaging readouts yields a multimodal profile that better characterizes active neuroinflammatory states and may inform anti-inflammatory or disease-modifying treatment strategies (145)

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The first GLP-1 drug was called Byetta or exenatide, and FDA officials approved it in 2006

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Further integrative analysis applied weighted gene co-expression network analysis (WGCNA) to identify co-regulated gene modules within each brain region