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These cellular sources include: Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs): These highly proliferative and neurotrophic stem cells secrete brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF), improving synaptic plasticity and neuronal survival in regions linked to sleep regulation, such as the hypothalamus and brainstem

Its ability to trigger AMPK activation and downstream gene programs (PGC-1, Nrf2) makes it ideal for experiments on metabolic syndrome, type-2 diabetes models, and longevity assays

MTHFR variants are genetic mutations that can disrupt the metabolism of folate and other B vitamins, leading to increased levels of homocysteine in the blood

Increased RAB31 Expression in Cancer-Associated Fibroblasts Promotes Colon Cancer Progression Through HGF-MET Signaling