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Lentiviral gene transduction The shRNA sequence against SRD5A1, that is CTCGAGTGCTGTTGACAGTGAGCGACCTGTACCTGTTATCAATATATAGTGAAGCCACAGATGTATATATTGATAACAGGTACAGGCTGCCTACTGCCTCGGAGAATTC, was cloned into TRIPZ vector (Thermo Fisher Scientific, USA), which provides inducible shRNA expression in the presence of doxycycline (Dox)

PLoS ONE, 7 , e42017

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Apoptosis and the ensuing growth of cells have been linked to high expression of the pro-apoptotic protein Bax (221)

Serum vitamin B 12 levels in individuals with the TT genotype (388.42 213.20 pg/mL) were lower than in patients with the CC genotype (599.73 265.99 pg/mL) or the CT genotype (498.25 235.66 pg/mL)