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Funding This work was supported by the National Natural Science Foundation of China (82172656, 81902550, 81802476), and the Natural Science Foundation of Hunan Province (2021JJ40882)

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Skin Health Research Skin research represents the most extensively documented application area for GHK-Cu in laboratory studies focused on skin rejuvenation mechanisms

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Subsequently, IMM localized cytochrome P450 family 27 subfamily A member 1 (CYP27A1) converts cholesterol to oxysterols such as (25 R )26-hydroxycholesterol and 3-hydroxy-5-cholesten-(25 R )26-oic acid