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Physiologically, patients with asthma frequently experience disruptions in their melatonin levels, namely a delayed acrophase in peak serum concentrations, as well as in the amount of GSH produced in the lung ( In clinical practice, melatonin is often prescribed at a dose of 2mg for the average (70kg) human adult (69)

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doi: 10.1093/nar/gky682 89 HardikarSYingZZengYZhaoHLiuBVelandNet al

TABLE 1 Summary of RDP human clinical studies on Pycnogenol sorted by applications and by year of publication

Conclusion Skin whitening treatments can be a viable option for those seeking a lighter complexion, but it's essential to approach them with caution and prioritize safety