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Similar to ICARIA-MM, the primary endpoint was PFS

However, over-exercising can have side effects if you have other health conditions like adrenal fatigue , so it is important to seek guidance from a medical professional before increasing your physical activity if you have preexisting health conditions

It interacts with integrins and other focal adhesion proteins such as paxillin, regulatory enzymatic signalling molecules such as PI3K, SH3 domain-containing adapter proteins, and other tyrosine kinases via an autophosphorylation site at tyrosine residue 397 (pY397)