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A special case is an epididymal tissue, which synthesizes GPX3 and releases it into a cavity, where sperm storage takes place ( GPX3 is not characteristic in transcriptional regulation, and the upregulation of GPX3 expression under inflammatory conditions is thought to be due to oxidative stress

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In somatic cells of XX individuals, one X chromosome undergoes transcriptional silencing, ensuring that most X-linked genes are expressed equally from the single active X chromosome in both XX and XY cells