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Moreover, insulin signaling appears to be relevant for the adaptative ER stress response in DKD

Electron transport chain A series of transmembrane protein complexes, present on the inner membrane of mitochondria, that transfer electrons via redox reactions to the terminal electron acceptor oxygen, which is reduced with binding of protons to a water molecule

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2-AR activation not only drives MDSC expansion but also increases their mobilization from the bone marrow into the vasculature, exacerbating their accumulation in tumors [120]

It has been demonstrated that the activation of the mTORC1 pathway is associated with cancer cells' dependence on glutamine [97]