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This was observed in primary fibroblasts from FXTAS-affected subjects ranging from stages 2.5 to 5

Cell Signal 14(4):285295

5-Amino-1MQ is a small-molecule quinolinium compound not a peptide that selectively inhibits nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme involved in the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor

Here in this study, the authors revealed that this plant extract increased the concentration of GABA by 240% in groups treated with 4 and 8 mg/kg, which is almost 3-fold higher than the increase in the sodium valproate group (96%)