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195,290,291 Wang et al

The chk1 pathway is required to prevent mitosis following cell-cycle arrest at start

Upregulation of CD38 in patients with SSc, resulting from its induction by cytokines such as TGF-, IL-6 and senescent cell-derived SASP enriched in the fibrotic tissue microenvironment, will promote NAD + consumption and decline, which in turn impairs the function of sirtuins and other NAD + -dependent cellular enzymes

Sepsis attracts the attention of clinicians and researchers due to the poor prognosis of patients in critical care medicine (Fleischmann et al., 2016a