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We tested the role of integrin 1, dominantly expressed in various organoid models (Extended Data Fig

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The liver is the principal site for the hydroxylation of cholecalciferol at carbon 25 by 25-hydroxylase enzymes (CYP2R1 and CYP27A1) to form 25(OH)VD 3

8 Functions of GSH in redox buffering, detoxification, and drug resistance Glutathione (GSH) is the principal intracellular redox buffer that preserves cellular homeostasis through detoxification of ROS and regeneration of antioxidant capability via GR-catalyzed recycling of its oxidized form (GSSG)

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