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The EAT protocol includes, amongst others, the use of hamster-derived S9-fraction for preparation of S9-mix, as it contains higher levels of certain CYPs relevant for metabolic activation of NAs, compared to the standard rat S9-fraction

To view a copy of this license, visit About this article Cite this article Ortega, M.A., lvarez-Mon, M.A., Garca-Montero, C

In fact, diabetes induces an alteration in the activity of glutathione peroxidase and reductase to maintain a normal GSH level in order to avoid the increase of nitric oxide and the risk of thrombosis

This is consistent with experimental data in mice [17,18] and in the human study [19]

doi: 10.22074/cellj.2022.7907, 47