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In the ob / ob mice, daily treatment with perindopril, an angiotensin-converting enzyme inhibitor (ACEI), or telmisartan, an angiotensin receptor blocker (ARB), but not amlodipine, an L-type calcium channel blocker (CaB), significantly inhibited DPN development without affecting the hyperglycemia

It is an inflammatory and neurodegenerative disorder driven by extracellular accumulation of amyloid- (A) and intracellular aggregation of Tau protein (118)

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To achieve maximum effect, it is recommended to integrate the ampoule into your daily routine after the toning stage, distributing the product with gentle motions over the face, neck, and dcollet area

la Marca G, Malvagia S, Pasquini E, Innocenti M, Donati MA, Zammarchi E