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Doubling doses increases injection site reactions and transient side effects without meaningful metabolic benefit

Accumulation of RNA-dependent protein kinase (PKR) in the nuclei of lung cancer cells mediates radiation resistance

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This phenomenon was more evident at the later disease stage and aligned with findings by McDonald and colleagues 26 , who demonstrated altered glucose homeostasis and uptake in G93A-SOD1 mice, attributed to the hormonal regulation of glucose concentrations, which may contribute to disease progression

Both free Rifs solution and Rif-SLNs exhibited MIC values of 8 g/mL and 4 g/mL, respectively, suggesting the superior effectiveness of Rif-SLNs compared to free rifampicin