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Indeed, reports suggest that CGRP is increased in the bronchoalveolar lavage fluid of asthmatics and might contribute to the late phase asthmatic reactions following provocation by allergen inhalation [148]

Atayde VD, Jasiulionis MG, Cortez M, Yoshida N

As a catalytic cofactor, zinc is involved in all six enzyme classes (oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases), either directly driving bond-making and bond-breaking reactions at the active site (catalytic zinc) or enhancing enzymatic activity in multi-metal systems, where zinc collaborates with other metal ions positioned in close proximity, one serving a catalytic role while others modulate activity (cocatalytic zinc) (15)

doi: 10.1892/0891-6640(2005)19 2.0.co;2

Yesiladali M, Yazici MGK, Attar E, Kelestimur F