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Rather than working with a crude tissue extract, researchers synthesised a short, chemically defined tetrapeptide of reproducible composition, which makes quality control and experimental reproducibility easier

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After activation, platelets in PRP can release a variety of growth factors, including transforming growth factor (TGF), platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), basic fibroblast growth factors, vascular endothelial growth factor (VEGF), epidermal growth factors, and many others