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doi: 10.1016/0014-4827(54)90169-X 43 MillerRKGenbacevOTurnerMAAplinJDCaniggiaIHuppertzB

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Several factors, including dosage, administration route, vehicle of administration, colon microbiota, diet, food matrix, and sex differences, contribute to the variability in flavonoid absorption ( In addition to the hydrolysis of flavonoid glycosides, the cecal microflora also plays a role in breaking down monomeric flavonoids into monophenolic acids