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Description

10.1007/s10565-015-9296-7 95 MehmoodT.MaryamA.GhramhH

PMCID: PMC8789089

John Blake Publishing

Treasure Island, FL: StatPearls

This B12-IF complex reaches the terminal ileum, where it binds to heterodimeric receptors cubam composed of an outer protein cubulin and transmembrane protein amnionless , located on the surface of polarized epithelial enterocytes in the apical brush border ( In the bloodstream, free B12 may be bound by HC or transcobalamin (TC)