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149 Results from several meta-analyses identified that there are groups with an increased risk of B12 deficiency, namely those with pre-existing moderately low vitamin B12 levels 71 or those aged 60 years, and/or on 2000 mg/day metformin and/or 3 years of treatment

Gastrointestinal issues A vitamin B12 deficiency can cause a range of gastrointestinal issues due to the resulting lack of red blood cells [4]

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Copper peptides degrade rapidly at room temperature studies using HPLC tracking found potency drops to 7075% at 14 days refrigerated and below 60% at 21 days