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doi: 10.1007/s11154-019-09513-z 36 ConnorsJDaweNVan LimbergenJ

Stimulating both pathways simultaneously produces synergistic GH release stronger than either compound alone

Fasting glucose deserves periodic attention as well, because GH secretagogues can produce mild insulin resistance, most notably at higher doses

BACH1 interacts directly with the insulin receptor (IR) along with the proteintyrosine phosphatase 1B (PTP1B), which dephosphorylating the insulin receptor (IR) to repress IRinduced insulin signaling