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doi: 10.1016/0022-1759(79)90133-9

In a recent study, Glo proteins were coupled to the Tat (transactivator of transcription) peptide as a vehicle to provide Glo-1 and Glo-2 exogenously to cells of the central nervous system (Shin et al., 2014)

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Krauth-Siegel et al., studied the Y197S variant of GR and concluded the diminished accumulation of FAD-NADPH charge transfer and the overall decrease in the rate constants observed for reduction were evidence of Y197 directly participating in the flavin reduction event ( To determine the functionality of the Y296 residue in SmTGR, a study of the reductive half-reaction of the Y296A variant was performed

Notably, BSO also caused the accumulation of mitochondrial ROS and lipid peroxides in a time- and concentration-dependent manner, and their accumulations took place nearly at the same time (Fig