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Oral Recombinant Methioninase (O-rMETase) Is superior to Injectable rMETase and Overcomes Acquired Gemcitabine Resistance in Pancreatic Cancer

Eur Heart J 2023;44:26982709

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doi:10.1186/s12879-017-2253-8 Palamara AT, Nencioni L, Aquilano K,et al

This disruptor increased SOD-like activity (increasing the concentration of hydrogen peroxide) and suppressed catalase-like activity, enhancing the overall cellular level of hydrogen peroxide and supporting the efficacy of chemodynamic therapy