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Moreover, GDNF is not only essential for formation of the ENS, but its availability also determines the total number of enteric neurons in both colon and small bowel

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In nonenzymatic lipid peroxidation, ACSL4 conjugates polyunsaturated fatty acid (PUFA) to coenzyme A (CoA) to form PUFA-CoA, which lysophosphatidylcholine acyltransferases re-esterify into phospholipids [10] and enhanced invasiveness in cancers such as colorectal cancer [30]