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ASIC1a is a proton-gated Na + and Ca 2+ ion channel that can be activated in response to acidic pH (Yermolaieva et al., 2004), and it has been shown to participate in seizure termination by activating hippocampal inhibitory interneurons, which exhibited larger H+-gated densities than excitatory pyramidal neurons (Ziemann et al., 2008)

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CrossRef Difficult to treat and refractory autoimmune hepatitis: Recent advances in pharmacological management Sayan Malakar, Umair Shamsul Hoda, Suprabhat Giri, Arghya Samanta, Akash Roy, Rajat Gupta, S Rakesh Kumar, Mayank Agarwal, Anubhav Pawar, Sumit Rungta, Uday C Ghoshal World Journal of Hepatology .2025;[Epub] CrossRef Mechanistic optimization of inavolisib combined with CDK4/6 inhibitors in the treatment of PIK3CA-mutated breast tumors Rongyu Zhu, Haixin Zhang, Fuli Zhang Frontiers in Immunology .2025;[Epub] CrossRef Autoimmune hepatitis: current concepts in epidemiology, diagnosis, and management Brian J

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