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Huang, L.P., Lyu, S.C., Clayberger, C

More serious complications of a B12 deficiency include heart disease, infertility, coordination problems, neurocognitive disorders, peripheral neuropathy and vision loss

Nat Rev Endocrinology

For further studies we suggest to involve complexes 1 and 3 , possessing strongly bound ligands, as suitable model complexes both biologically relevant oxidation states +II and +III, with good solubility in water and biological media