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Research protocols typically use one approach or the other based on whether the model benefits from direct IGF-1 receptor agonism or physiological GH restoration

Horowitz MB, Levy EI, Kassam AB, Purdy PD

Burcham PC, Harman AW (1991) Acetaminophen toxicity results in site-specific mitochondrial damage in isolated mouse hepatocytes

Generative AI statement The author(s) declared that Generative AI was used in the creation of this manuscript

That selectivity profile is why ipamorelin became the default GHS-R compound for research protocols: you get the GH signal without the hormonal noise that comes with older GHRPs