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(139) described transcriptional changes in the brain of IF mice and found that the brain transcriptome of AL group mice exhibited strong, sustained upregulation of deleterious genetic pathways under ischemic stroke, but the activation of these pathways was suppressed in the IF 16 h group

H., Schug, B

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Symptom Overview Damage to motor, sensory, or autonomic nerves secondary to antineoplastic chemotherapy can result in varying degrees of dysfunction and/or pain, which can lead to significant morbidity and diminished quality of life for affected patients, with up to 70% of patients having some element of chemotherapy-induced peripheral neuropathy (CIPN) after chemotherapy

After binding of oxygen, the molecule switches from T, which has a low affinity for oxygen, to R state which has high oxygen affinity (56)