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doi: 10.3390/brainsci7020020

201 In breast cancer, elevated HSP90 levels stabilize estrogen receptor (ErbB)-dependent PI3K/AKT and ERK signaling pathways, counteracting the effects of hormonal therapies such as fulvestrant

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Studies show that CrAT overexpression in primary human skeletal myocytes increases glucose uptake and attenuates lipid-induced suppression of glucose oxidation, demonstrating the importance of carnitine-dependent metabolic pathways in preserving insulin sensitivity and metabolic health