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The antigen may be an autoantigen expressed during T cell development and tolerance and a foreign antigen present during normal immune processes

These findings necessitate further validation in future research (234, 235)

Supplementary Materials Data Availability Statement The survey and the detailed results are available in Datasets S1S3.

Adoption of an extended conformation by the P-segment has been suggested significant in forming binding pocket

[Google Scholar] The role of oxidative stress in diabetic neuropathy: generation of free radical species in the glycation reaction and gene polymorphisms encoding antioxidant enzymes to genetic susceptibility to diabetic neuropathy in population of type I diabetic patients